Identification, Symptoms and uses of Salicylic Acid
Ritik Shikhar Jain, Paresh. A. Patil
Department of Pharmaceutical Chemistry, VEWS Ahinsa Institute of Pharmacy, Dondaicha Dist. Dhule
*Corresponding Author E-mail: ritikbadera390@gmail.com
ABSTRACT:
In recent dates too many chemical are available in market which have Pharmaceutical uses as well as side effect. from that salicylic acid is also one of the chemical which use in number of treatments of diseases. But due to improper knowledge regarding their uses and side effect people avoid the use of SA. Identification of chemicals is very important factor because as we already know that thousands of chemicals are available in market for correct identification become very difficult. So for identification we refer various characteristic properties like colour, odour, solubility, pH etc.
Side Effect of salicylic acid:
1) Prolonged erythema [1]
2) Intense exfoliation [1]
3) Crusting [1]
4) Dryness [1]
5) Pigmentary dyschromias [1]
6) Systemic toxicity, salicylism [1]
7) Hypoglycemia [1]
8) Contact sensitization [1]
9) Difficult breathing [2]
10) Dryness and peeling of skin [2]
11) Fainting [2]
12) Hives or itching [2]
13) Redness of the skin [2]
14) Swelling of the eyes, face, lips, or tongue [2]
15) Tightness in the throat [2]
16) Unusually warm skin [2]
What happens if I overdose?
An overdose of salicylic acid is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed. [2]
Symptoms of overdose:
1) Confusion [2]
2) Diarrhea [2]
3) Dizziness [2]
4) Fast or deep breathing [2]
5) Headache (severe or continuing) [2]
6) Hearing loss [2]
7) Lightheadedness [2]
8) Nausea [2]
9) Rapid breathing [2]
10)Ringing or buzzing in the ears (continuing) [2]
11)Severe drowsiness [2]
12)Stomach pain [2]
13)Vomiting [2]
Physical Properties:
Theses Physical Properties play an important role in identification of Salicylic Acid which are below given:
1. Salicylic Acid has the appearance of a colourless crystalline powder.[3]
2. It is odourless or may have a slight phenolic odour.[3]
3. It has a sweetish taste.[3]
4. It has a melting point of 159°C and a sublimation point of 76°C.[3]
5. Its relative density is 1.4 compared to water which has a relative density of 1.[3]
6. Its solubility in water is 0.2g/100 ml at 20°C. [3]
7. It is soluble in alcohol, ether, boiling water.[3]
8. It has a pH of 2.4.[3]
9. It is a polar molecule which explains its low solubility in water.[3]
10. It was a molar mass of 138.1g/mol.[3]
11. Its chemical formula is C6H4(OH)COOH and an empirical formula of C7H6O3.[3]
12. It will auto-ignite at as low as 540°C. It is a relatively stable compound but oxidizing agents, strong bases, iodine, and fluorine may cause strong reactions.[3]
13. It is also sensitive to light.[3]
14. It can be harmful if inhaled, ingested or absorbed through skin.[3]
15. It is an irritant.[3]
Uses:
1) It is used as anti-inflammatory agent.[3]
2) It can be used in the treatment of warts.[3]
3) It can also be used as a comedolytic agent.[3]
4) It is also used as a analgesic.[3]
5) It is uses in aches and reduces the pain.[3]
6) It is used in fever treatment.[3]
REFERENCE:
1. Dove Press, "Clinical, Cosmetic and Investigational Dermatology", Published online 2015Aug26 by "Tasleem Arif"
2. Medically reviewed by Drug.com on April 17, 2017, written by cerner multum.
3. http://www.ukessays.com/essays/biology/history-of-salicylic-acid-biology-essay.php
Received on 29.12.2019 Modified on 30.01.2020
Accepted on 25.02.2020 ŠAJRC All right reserved
Asian J. Research Chem. 2020; 13(1): 71-72.
DOI: 10.5958/0974-4150.2020.00015.2